Coligranuloma :

        Sporadic disease of adult birds :

Symptoms :

• Low performance in older birds or high mortality in younger birds
• Respiratory distress
• Enteritis ( diarrhoea )

PM lesions :

• Cauliflower like nodules or millet sized nodules ( granuloma ) on viscera in entire intestine, liver, lungs and kidney
• Omphalitis in chicks – discoloured and misshapen yolk ( mushy chick) are seen.

Microscopic :

• The section of nodules shows caseous necrosis in the centre covered by macrophages, lymphocytes and giant cells, as in tuberculosis.
• Organism is demonstrated by GM staining.