About Lesson
Reactions promoted by radiations
- UV light induces the condensation of two ethylene group to form a cyclobutene ring.
i.e. Adjacent pyrimidine –— radiation– > cyclobutene pyrimidine dimers.
- Ionization radiations can cause ring opening and fragmentation of bases.
Note: DNA –Replication – DNA
DNA — Transcription —> RNA – Translation —> Protein
- Alkylating agents can alter certain bases of DNA.
- Dimethyl suphate can methylate a guanine to yield O6-methylguanine which can’t base pair with cytosine.